Why do I get lots of them?
There is a genetic predisposition to multiple SKs in around half of affected people.
A common question is “What can I do to stop getting them?”
It could be said that such a treatment would have enormous demand. Traditionally, you either put up with them or arrange to have them removed as a cosmetic procedure. There is some evidence that ammonium lactate or tazarotene 0.1% cream may reduce the height or improve the appearance of individual lesions.
Unfortunately, there is currently no treatment that has been truly proven to work. There will surely be a topical product in the future that will work – but when is anyone’s guess. Research has recently found that the lesions “are sensitive to inhibition by ATP-competitive Akt inhibitors” which should lead to new topical products.
Leser-Trélat described The sudden eruption of large numbers of inflamed SKs in association with internal malignancy. This has been described in case reports and it is still not known whether this is truly an association. However, it usual to run some cancer tests in younger people with the sudden eruption of multiple SKs.